Department of Surgery and Cancer, Imperial College, London, UK. Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK. Division of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK. PsychoNeuroEndocrinology Research Group, Centre for Neuropsychopharmacology, Division of Psychiatry and Computational, Cognitive and Clinical Neuroimaging Laboratory, Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK. Imperial College London, Department of Public Health, Imperial Clinical Trials Unit, London, UK. Diabetes Complications Research Center, University College Dublin, Ireland. Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia. Southampton Health Technology Assessment Center, University of Southampton, Southampton, UK. Section of Nutritional research, Department of Metabolism, Digestion and Reproduction, Imperial College London, UK. Department of Endocrinology, King's College Hospital NHS Trust, London, UK. University Hospital Southampton NHS Foundation Trust, Biomedical Research Center, Southampton, UK. Primary Care, Population Sciences and Medical Education, University of Southampton Medical School, Southampton, UK.